Klary-500

Composition:

• Clarithromycin 500 mg

Description:

Klary 500 contains Clarithromycin, a macrolide antibiotic with powerful antibacterial properties. It is widely used to treat various bacterial infections by inhibiting the production of essential proteins in bacteria, thereby preventing their growth and proliferation.

Indications:

Klary 500 is prescribed for the treatment of:

• Respiratory Tract Infections:
  • Community-acquired pneumonia
  • Chronic bronchitis exacerbations
  • Sinusitis
  • Pharyngitis
  • Tonsillitis
• Skin and Soft Tissue Infections:
  • Folliculitis
  • Abscesses
  • Cellulitis
• Helicobacter pylori-Associated Peptic Ulcers:
  • Used as part of triple therapy in combination with proton pump inhibitors and other antibiotics.
• Ear Infections:
  • Otitis media.
• Mycobacterial Infections:
  • Prophylaxis and treatment of Mycobacterium avium complex (MAC) in HIV patients.

Benefits:

• Effective against a wide range of gram-positive and some gram-negative bacteria.
• Suitable for patients allergic to penicillins.
• Longer Half-Life: Requires fewer doses compared to other antibiotics.
• High Tissue Penetration: Ensures rapid relief from infection.
• Part of the first-line treatment for H. pylori infections.

Dosage and Administration:

• Adults: Typically, 500 mg twice daily for 7-14 days.
• H. pylori eradication therapy: 500 mg twice daily in combination with other medications for 7-14 days.
• Dosage may vary based on the severity of the infection and patient condition.
• Take with or without food but maintain consistent intervals between doses.

Storage Instructions:

• Store at room temperature (below 30°C).
• Protect from moisture and sunlight.
• Keep out of reach of children.

Precautions:

• Allergy: Not suitable for patients allergic to macrolides or clarithromycin.
• Drug Interactions: May interact with drugs such as:
  • Statins (risk of muscle damage).
  • Anticoagulants (increased risk of bleeding).
  • Ergot alkaloids.
  • QT-prolonging medications.
• Use with caution in patients with:
  • Hepatic or renal impairment.
  • History of QT interval prolongation or arrhythmias.
• Avoid alcohol during treatment.

Side Effects:

• Common:
  • Nausea, vomiting, diarrhea, abdominal pain, altered taste.
• Less Common:
  • Headache, dizziness, fatigue.
• Rare but Serious:
  • Allergic reactions (rash, swelling, difficulty breathing).
  • Severe diarrhea (Clostridium difficile-associated).
  • Liver dysfunction or jaundice.
  • QT prolongation leading to arrhythmias.

Key Notes:

• Complete the full course as prescribed to prevent antibiotic resistance.
• Avoid skipping doses to ensure treatment effectiveness.
• Consult your healthcare provider immediately in case of side effects or lack of improvement.

This formulation is a potent and reliable option for addressing bacterial infections, ensuring fast recovery and optimal patient outcomes.