LeFlox-500

Composition:

• Levofloxacin 500 mg

Description:

LeFlox 500 is a broad-spectrum fluoroquinolone antibiotic containing Levofloxacin, an active compound that is effective in treating a wide range of bacterial infections. By inhibiting bacterial DNA synthesis, Levofloxacin prevents the bacteria from reproducing and spreading, thereby helping the body to fight off the infection.

Indications:

LeFlox 500 is commonly prescribed for the treatment of:

• Respiratory Tract Infections:
  • Community-acquired pneumonia
  • Chronic obstructive pulmonary disease (COPD) exacerbations
  • Acute bacterial sinusitis
  • Acute bronchitis
• Urinary Tract Infections:
  • Cystitis
  • Pyelonephritis
• Skin and Soft Tissue Infections:
  • Cellulitis
  • Wound infections
• Gastrointestinal Infections:
  • Enteric fever (typhoid fever)
• Other Infections:
  • Prostatitis
  • Intra-abdominal infections (in combination with other antibiotics)

Benefits:

• Broad-spectrum activity: Effective against both gram-positive and gram-negative bacteria, including resistant strains.
• Convenient dosing schedule: Typically administered once or twice a day for quick relief.
• Effective against complicated infections: Particularly useful for treating respiratory and urinary tract infections.
• Suitable for patients with penicillin allergies or those requiring a non-penicillin alternative.

Dosage and Administration:

• Adults: Usually 500 mg once a day for 7-14 days depending on the severity of the infection.
• For severe infections, a higher dose may be recommended.
• Acute bacterial exacerbations: 500 mg once a day for 7 days.
• Urinary tract infections: 250 mg to 500 mg once daily for 3-7 days.
• Dosage may vary based on the infection type and patient condition. Always follow the doctor’s prescription.
• Can be taken with or without food.

Storage Instructions:

• Store at room temperature (below 30°C).
• Protect from moisture and sunlight.
• Keep the bottle tightly closed and out of reach of children.

Precautions:

• Allergy: Not recommended for patients allergic to Levofloxacin or other fluoroquinolones.
• Drug Interactions: Be cautious with drugs like:
  • Antacids, sucralfate (may interfere with absorption).
  • Anticoagulants (increased risk of bleeding).
  • Other QT-prolonging medications.
• Caution in certain conditions:
  • Renal impairment (adjust dosage as necessary).
  • History of tendon disorders (may increase the risk of tendonitis or tendon rupture).
  • Pregnancy and breastfeeding: Not recommended unless clearly needed.

Side Effects:

• Common:
  • Nausea, vomiting, diarrhea
  • Dizziness, headache
  • Abdominal discomfort
• Less Common:
  • Insomnia, rash, itching
  • Taste disturbance
• Serious Side Effects:
  • Tendonitis or tendon rupture (particularly in elderly patients).
  • QT prolongation leading to arrhythmias.
  • Severe allergic reactions (rash, swelling, difficulty breathing).
  • Liver damage (elevated liver enzymes).
  • Severe diarrhea (Clostridium difficile-associated).

Key Notes:

• Always complete the full course of antibiotics, even if you feel better, to avoid antibiotic resistance.
• If you experience side effects or have concerns, contact your healthcare provider immediately.
• Drink plenty of fluids while on the medication.
• Avoid excessive sun exposure during treatment, as Levofloxacin can increase the risk of sunburn.