TamZen-D

Composition:

• Tamsulosin 0.4 mg (SR) (Sustained Release)
• Dutasteride 0.5 mg

Description:

TamZen D is a combination medication formulated to address symptoms of benign prostatic hyperplasia (BPH) in men. It combines the alpha-blocker Tamsulosin, which relaxes the muscles in the prostate and bladder neck, and Dutasteride, a 5-alpha reductase inhibitor that reduces the size of the prostate gland over time.

This dual-action therapy provides both immediate symptom relief and long-term benefits in reducing prostate enlargement.

Indications:

TamZen D is indicated for:

• Benign Prostatic Hyperplasia (BPH):
  • Relief from lower urinary tract symptoms (LUTS), such as:
    • Difficulty in urination.
    • Frequent urination, especially at night.
    • Incomplete bladder emptying.
  • Prevention of acute urinary retention (AUR).
  • Reducing the need for surgical intervention in BPH.

Benefits:

1. Symptom Relief:
   • Tamsulosin ensures smooth urinary flow by relaxing muscles in the prostate and bladder.
2. Prostate Size Reduction:
   • Dutasteride helps shrink the prostate gland, improving symptoms over time.
3. Prevention of Complications:
   • Reduces the risk of urinary retention and surgery for BPH.
4. Convenient Dosage:
   • Single-tablet therapy eliminates the need for multiple medications.

Dosage and Administration:

• Recommended Dosage: One tablet daily, preferably after a meal, at the same time each day.
• Swallow whole; do not crush or chew.
• Duration of therapy is based on the physician’s assessment of symptom severity and prostate size.

Precautions:

• Allergies: Avoid in patients allergic to Tamsulosin, Dutasteride, or other ingredients in the tablet.
• Pregnancy and Women Handling:
  • Dutasteride can be absorbed through the skin and may harm a developing fetus. Pregnant women should avoid handling broken or crushed tablets.
• Blood Donation: Avoid donating blood while on Dutasteride and for 6 months after stopping treatment to prevent exposure to pregnant recipients.
• Liver Disorders: Use with caution in patients with liver impairment.

Side Effects:

• Common:
  • Dizziness or fainting (especially when standing up).
  • Ejaculation disorders.
  • Decreased libido.
  • Breast tenderness or enlargement.
• Rare but Serious:
  • Severe allergic reactions (swelling, rash, difficulty breathing).
  • Persistent painful erection (priapism).

Storage Instructions:

• Store in a cool, dry place below 30°C.
• Protect from light and moisture.
• Keep out of reach of children.

Key Notes:

• Regular follow-ups with a physician are necessary to monitor prostate size and symptoms.
• Not intended for use in women or children.
• May take several months to achieve maximum therapeutic benefits.