LeZolid-600

Composition:

• Linezolid 600 mg

Description:

LeZolid 600 contains Linezolid, a synthetic antibiotic belonging to the oxazolidinone class, designed to combat serious bacterial infections caused by gram-positive organisms. It works by inhibiting bacterial protein synthesis, effectively stopping the growth of bacteria.

Indications:

LeZolid 600 is prescribed for the treatment of:

1. Complicated Skin and Soft Tissue Infections:
   • Cellulitis, abscesses, and diabetic foot infections.
2. Nosocomial Pneumonia:
   • Hospital-acquired infections, including those caused by resistant strains.
3. Community-Acquired Pneumonia (CAP):
   • Effective against streptococci and other gram-positive bacteria.
4. Vancomycin-Resistant Enterococcal (VRE) Infections:
   • Bacteremia and other resistant enterococcal infections.
5. Methicillin-Resistant Staphylococcus aureus (MRSA):
   • Particularly effective for difficult-to-treat MRSA cases.

Benefits:

• Targets drug-resistant bacteria like MRSA and VRE.
• Excellent bioavailability (can be administered orally or intravenously).
• Well-tolerated for long-term therapy in chronic infections.
• Effective against a broad spectrum of gram-positive pathogens.

Dosage and Administration:

• Adults:
  • Typically 600 mg every 12 hours for 10-14 days.
  • Duration varies depending on infection type and severity.
• Administration:
  • Can be taken with or without food.
  • Ensure adherence to the prescribed schedule for optimal results.

Storage Instructions:

• Store at room temperature (15°C–25°C).
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Precautions:

• Blood Disorders: Regular blood count monitoring is recommended for prolonged treatment to prevent thrombocytopenia.
• Peripheral Neuropathy: Use cautiously in long-term therapy as it may cause nerve damage.
• Serotonin Syndrome: Avoid concomitant use with serotonergic drugs such as SSRIs or MAO inhibitors.
• Allergies: Contraindicated in patients with known hypersensitivity to Linezolid.
• Renal or Hepatic Impairment: Dose adjustment may be necessary.

Side Effects:

• Common:
  • Diarrhea, nausea, headache, and insomnia.
• Less Common:
  • Vomiting, rash, and dizziness.
• Serious:
  • Myelosuppression (anemia, thrombocytopenia).
  • Lactic acidosis (unexplained nausea, vomiting, or weakness).
  • Optic neuropathy with prolonged use.

Key Notes:

• Always complete the prescribed course to prevent antibiotic resistance.
• Regular follow-ups are essential for long-term use to monitor side effects.
• Inform your doctor about any concurrent medications to avoid interactions.

LeZolid 600 [Tab] offers a robust solution for managing severe and resistant bacterial infections, ensuring improved patient outcomes through targeted therapy.