LifeZone-S-1.5

Composition:

• Cefoperazone 1000 mg
• Sulbactam 500 mg
• W.F.I. (Water for Injection)

Description:

LifeZone S 1.5 is a combination antibiotic medication that pairs Cefoperazone, a third-generation cephalosporin, with Sulbactam, a beta-lactamase inhibitor. This combination is highly effective against a wide range of bacterial infections, including those caused by beta-lactamase-producing bacteria.

Indications:

LifeZone S 1.5 is indicated for the treatment of:

1. Respiratory Tract Infections:
   • Pneumonia
   • Bronchitis
2. Intra-Abdominal Infections:
   • Peritonitis
   • Biliary tract infections
3. Urinary Tract Infections (UTIs)
4. Skin and Soft Tissue Infections
5. Gynecological Infections:
   • Pelvic inflammatory disease
6. Bone and Joint Infections
7. Septicemia
8. Post-Operative Infections

Benefits:

• Broad-Spectrum Coverage: Effective against both gram-positive and gram-negative bacteria.
• Beta-Lactamase Protection: Sulbactam inhibits beta-lactamase enzymes, extending the activity of Cefoperazone.
• Rapid Action: Ensures faster resolution of bacterial infections.
• Versatile Administration: Can be used for severe and complex infections.

Dosage and Administration:

• Standard Dosage: 1.5 g (Cefoperazone 1 g + Sulbactam 0.5 g) every 12 hours.
• Severe Infections: Dose adjustments may be required based on the severity of the infection and patient response.
• Administration: To be given via intramuscular (IM) or intravenous (IV) injection as directed by a healthcare provider.

Storage Instructions:

• Store below 25°C in a dry place.
• Protect from light and moisture.
• Reconstituted solutions should be used immediately.

Precautions:

• Allergy: Contraindicated in patients allergic to cephalosporins or penicillins.
• Renal or Hepatic Impairment: Use with caution in patients with kidney or liver dysfunction.
• Pregnancy and Breastfeeding: Consult a doctor before use.
• Drug Interactions:
  • Avoid use with alcohol during and up to 72 hours post-treatment to prevent disulfiram-like reactions.
  • Monitor when co-administered with aminoglycosides or anticoagulants.

Side Effects:

• Common:
  • Diarrhea, nausea, vomiting, and injection site reactions.
• Rare:
  • Allergic reactions (rash, itching, swelling, difficulty breathing).
  • Liver enzyme elevation or jaundice.
  • Blood disorders (e.g., thrombocytopenia, anemia).

Key Notes:

LifeZone S 1.5 is a powerful solution for combating severe bacterial infections, particularly in hospital and critical care settings. Its combination of Cefoperazone and Sulbactam ensures effective treatment even against resistant bacterial strains. Always use as prescribed to maximize its benefits and minimize the risk of resistance.