NiSol-500

Composition:

• Methylprednisolone 500 mg

Description:

NiSol 500 is an injectable formulation containing Methylprednisolone, a potent corticosteroid with anti-inflammatory and immunosuppressive properties. It is widely used to treat a variety of conditions associated with inflammation and immune system dysfunction.

Indications:

NiSol 500 is prescribed for:

• Severe Allergic Reactions:
  • Anaphylaxis
  • Drug-induced allergies
• Autoimmune Disorders:
  • Systemic Lupus Erythematosus (SLE)
  • Rheumatoid Arthritis
  • Multiple Sclerosis flares
• Skin Disorders:
  • Psoriasis
  • Severe dermatitis
• Respiratory Conditions:
  • Severe asthma
  • Chronic obstructive pulmonary disease (COPD) exacerbations
• Shock and Critical Illness:
  • Septic shock
  • Adrenal insufficiency crises
• Organ Transplantation:
  • Prevention and treatment of rejection episodes.

Benefits:

• Rapid Action: Immediate relief of severe inflammatory and immune reactions.
• Multi-Use Applications: Suitable for various systemic and localized conditions.
• Reliable: Proven efficacy in critical and emergency care.
• Convenient Dosage Form: Ampoule for precise administration in medical settings.

Dosage and Administration:

• Administered via intravenous (IV) or intramuscular (IM) injection by healthcare professionals.
• Dosage varies depending on the condition and severity:
  • Usual dose: 500 mg once daily or as directed by the physician.
• Monitor patient response and adjust dose as needed.

Storage Instructions:

• Store below 25°C.
• Protect from light and moisture.
• Keep out of reach of children.

Precautions:

• Contraindications:
  • Hypersensitivity to methylprednisolone or corticosteroids.
  • Systemic fungal infections.
• Use with caution in patients with:
  • Diabetes Mellitus: May increase blood glucose levels.
  • Hypertension: Risk of fluid retention.
  • Peptic Ulcers: Can exacerbate symptoms.
  • Osteoporosis: Long-term use may weaken bones.
• Avoid abrupt withdrawal; taper dose under medical supervision.
• Not suitable for long-term use unless prescribed.

Side Effects:

• Common:
  • Nausea, headache, dizziness, increased appetite.
• Serious:
  • Hyperglycemia, hypertension, fluid retention, infections, mood changes.
• Rare but Severe:
  • Adrenal suppression, bone fractures, gastrointestinal bleeding.

Key Notes:

• Only for short-term use unless specified for chronic conditions.
• Monitor blood pressure, glucose levels, and signs of infection during use.
• Regular follow-up with the physician is necessary for optimal management.