SAM-400

Composition:

• S-Adenosyl L-Methionine 400 mg

Description:

Sam 400 contains S-Adenosyl L-Methionine (SAMe), a naturally occurring compound in the body that plays a critical role in various biochemical processes, including the synthesis of neurotransmitters and the regulation of liver function. This formulation offers 400 mg of SAMe per tablet, providing therapeutic benefits that are widely recognized in the management of mood disorders, liver health, and joint pain.

SAMe is involved in methylation processes and supports cell regeneration, making it an essential compound for maintaining overall health. It is commonly used for its potential therapeutic effects in treating depression, liver disease, and osteoarthritis.

Indications:

Sam 400 is primarily indicated for:

• Mood and Mental Health:
  • As a natural supplement for the management of depression, anxiety, and stress. SAMe supports the production of neurotransmitters like serotonin, dopamine, and norepinephrine.
• Liver Health:
  • SAMe supports liver function by promoting the production of glutathione, a powerful antioxidant. It helps in treating liver diseases like hepatitis and fatty liver disease.
• Joint Health:
  • SAMe is beneficial in osteoarthritis management by reducing inflammation and improving joint mobility. It can also help with cartilage repair and may reduce pain associated with joint conditions.

Benefits:

• Supports Liver Function: Promotes liver health by increasing glutathione levels.
• Mood Improvement: Known for its antidepressant-like effects, SAMe boosts serotonin and dopamine levels, contributing to improved mood and mental well-being.
• Joint Health: Reduces inflammation, pain, and stiffness, particularly in osteoarthritis patients.
• Overall Wellness: As a potent methyl donor, it plays a role in cellular repair and maintenance.

Dosage and Administration:

• Adults: The typical dose for depression or joint health is 400 mg to 1200 mg per day, depending on the severity of the condition.
• For liver health, dosing may vary based on the recommendations of a healthcare provider.
• Take with food to improve absorption and reduce any potential gastrointestinal discomfort.
• It is advisable to start with a lower dose and gradually increase based on the body’s response.

Storage Instructions:

• Store in a cool, dry place, away from direct sunlight.
• Keep the container tightly closed to maintain its potency.
• Keep out of the reach of children.

Precautions:

• Allergic Reactions: Discontinue use if you experience signs of an allergic reaction, such as rash, itching, or difficulty breathing.
• Mental Health: While SAMe is commonly used for mood support, individuals with bipolar disorder should use it cautiously, as it may trigger mania.
• Pregnancy and Breastfeeding: Consult a doctor before use.
• Drug Interactions: May interact with antidepressants, SSRIs, or other mood-altering medications.
• Liver Issues: If you have pre-existing liver conditions, consult your healthcare provider before use.

Side Effects:

• Common:
  • Gastrointestinal upset (nausea, bloating, diarrhea).
  • Headaches.
• Rare but Serious:
  • Allergic reactions (rash, swelling).
  • Mania or hypomania in patients with bipolar disorder.

Key Notes:

• SAMe is well-tolerated but should be used as part of a comprehensive treatment plan under medical supervision.
• Gradual Improvement: It may take a few weeks to see the full benefits, especially for mood and joint health.
• Consult your healthcare provider before starting this supplement, especially if you are on medications or have pre-existing conditions.